AMD and Nutanix have entered into a multi-year strategic partnership aimed at developing an open, full-stack AI infrastructure platform built specifically to power agentic AI applications across enterprise, edge, and cloud environments. Through this collaboration, both companies are reinforcing their shared commitment to creating an open AI ecosystem that gives enterprises greater flexibility, performance, and deployment freedom.
Under this agreement, AMD and Nutanix will combine silicon innovation, open runtime software, and enterprise cloud orchestration capabilities to deliver scalable, production-ready AI platforms. Notably, they will optimize the Nutanix Cloud Platform and Nutanix Kubernetes Platform on AMD EPYC CPUs and AMD Instinct GPUs. At the same time, they will integrate the AMD ROCm software ecosystem and the AMD Enterprise AI platform into Nutanix AI’s full-stack solutions. As a result, customers will gain access to high-performance infrastructure designed for agentic AI workloads, supported by a broad ecosystem of OEM partners.
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In addition to technology collaboration, AMD will make a strategic investment of $150 million in Nutanix common stock at $36.26 per share. Furthermore, AMD will allocate up to $100 million to fund joint engineering efforts and go-to-market initiatives. This combined investment will accelerate the global adoption of AMD- and Nutanix-powered agentic AI platforms. The equity investment is expected to close in the second quarter of 2026, pending regulatory approvals and customary closing conditions.
“Enterprise customers need the freedom to run the models and workloads that matter most to their business, without compromise,” said Dan McNamara, senior vice president and general manager of Compute and Enterprise AI at AMD. “Through our partnership with Nutanix we’re building a scalable, full-stack AI platform rooted in openness, designed to give enterprises and service providers the flexibility to innovate, extend and grow AI deployments across Enterprises.”
Similarly, Nutanix emphasized the strategic importance of the collaboration. “Our partnership with AMD reflects a shared vision for scalable, production-ready AI infrastructure,” said Tarkan Maner, President and Chief Commercial Officer, Nutanix. “Together, we are delivering full-stack, integrated platforms optimized for inference and agentic applications across hybrid environments for enterprises and service providers.”
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Advancing the Open Ecosystem for Enterprise AI
As enterprise AI rapidly evolves, inference workloads are becoming the dominant driver of infrastructure demand. Consequently, organizations now require platforms that deliver performance, efficiency, and operational simplicity at scale. AMD continues to advocate for open standards, interoperable software frameworks, and architectural flexibility all critical elements for long-term innovation.
The first jointly developed agentic AI platform is expected to launch in late 2026, highlighting both companies’ focus on rapid execution. Importantly, the co-engineered solution will leverage AMD Instinct GPUs for high-performance inference acceleration and EPYC processors for high-core-density compute and orchestration. Meanwhile, Nutanix Enterprise AI will provide unified lifecycle management, enabling enterprises to deploy both open-source and commercial AI models without relying on vertically integrated AI stacks.
Ultimately, AMD and Nutanix are shaping a new generation of open AI infrastructure tailored for enterprise AI agents, multimodel inference services, and industry-specific intelligent applications.
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